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Chapter 27: Familial Cancer Syndromes: The Role of Caretakers and Gatekeepers

Contributors: Kenneth W. Kinzler, Bert Vogelstein

Abstract

The past decade has witnessed the elucidation of the specific genetic bases of nearly twenty inherited predispositions to cancer. This information not only is yielding immediate practical benefits in the form of genetic testing but also is providing important insights into mechanisms regulating cancer susceptibility.



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